Bridging the gap between engineered and native tissues.

The Lindberg Lab combines biology, chemistry, and engineering to develop treatments for musculoskeletal and hematological diseases like osteoarthritis and blood cancers. We focus on materials discovery and biofabrication with a particular interest in advancing next generation microphysiological systems (MPS), assembloids and organoids for tissue engineering and disease modelling. To ensure their research is clinically relevant, we use patient’s own cells and tissues, capturing a wide range of demographic differences to build smart, personalized models. Our overall goal is to identify therapeutic targets at a patient-specific level and to develop regenerative treatment options for musculoskeletal and hematological diseases that are effective across the wider population, including patients with compromised endogenous healing environments (e.g. chronic inflammation, diminished stem cell reserves, hypoxia, aging-related endocrine changes, and/or disrupted tissue homeostasis).