Mock Ambati Lab

Department of Bioengineering

The Ambati Lab

Molecular mechanisms of angiogenesis

Darker to lighter green gradient eye

OUR mission

Our mission is to understand, and develop interventions for vision loss.


We investigate the molecular mechanisms of angiogenesis, the growth of new blood vessels, in the cornea. Our laboratory group has solved the long-outstanding mystery of what keeps the cornea normally free of blood vessels, identifying the protein sVEGFR-1 as the prime mediator of this essential requirement for clear vision.

Research

Our lab has developed novel inhibitors targeting the key mediator of angiogenesis, VEGF, specifically sequestering this linchpin molecule within cells, complementing the existing anti-VEGF arsenal.

More about our research

a thin array electrode, shown with electrical boards and someone holding with a blue glove, in the Deku lab at the Knight Campus
A group of people in PPE in a lab

People

We are a team of bioengineers, neuroscientists and molecular biologists. 

Meet the Ambati Lab 

Resources

Explore resources from the Ambati Lab, and descriptions of courses that Dr. Ambati teaches. 

Resources from the Ambati Lab

Close-up shot of silicon wafer

Ambati Lab News

NSF GRFP awardees
Max receives the NSF GRFP!
Max receives the NSF GRFP for his proposal: "A Perfused Biohybrid Platform for Human Brain Organoid Research". Congrats, Max!
neural electrode in blue, with wires and chips
Knight Campus News Features Emma's Work
Knight Campus news features Emma's work on Iris128.
Felix Deki, Knight Campus courtyard
Knight Campus assistant professor Felix Deku awarded prestigious NIH grant
Felix Deku has been awarded an R01 grant from the National Institutes of Health (NIH) to support his innovative research in neuroengineering.
More News » 

The Ambati Lab 

In 2020, the Ambati Lab relocated to the University of Oregon's Phil and Penny Knight Campus for Accelerating Scientific Impact. Based in the Department of Bioengineering in Eugene, Oregon, the Amabti Lab explores mechanisms of corneal and retinal diseases and the development and improvement of therapies.