Keller Lab

Department of Bioengineering

The Keller Lab

Building better ultrasound tools for the diagnosis and treatment of disease 

Ultrasound doppler in green

Our mission is to understand and control how sound waves interact with living systems to enable new ways to diagnose and treat disease.

Ultrasound is widely used to create images of the body. In our lab, we go beyond imaging: we use carefully controlled sound waves to interact with tissues in targeted and measurable ways. These interactions can help clear infections, map tumor environments, deliver therapeutics, or stimulate immune responses. By integrating biological experiments, advanced imaging, and computational modeling, we study how mechanical forces generated by sound affect cells and tissue. This foundation in physics allows us to design ultrasound-based tools that are safe, precise, and adaptable across a wide range of medical applications.

 

 

Research

The Keller Lab develops image-guided ultrasound technologies to measure and control acoustic bioeffects in living systems. By combining ultrasound system design, cavitation imaging, contrast agent engineering, and biologically relevant models, we develop quantitative tools for applications ranging from drug delivery and biofilm treatment to tumor microenvironment sensing and super-resolution imaging.

Learn more about our therapeutic ultrasound research →

Video file
Sara Keller, with another woman holding a small glass vial in front of some equipment

People

We are always looking for intellectually curious, self-driven trainees who are eager to develop tools to understand and control how ultrasound interacts with biological systems. We foster a collaborative environment that empowers students and trainees from all backgrounds to learn, innovate, and develop the skills needed for successful careers as scientists and engineers. 

Meet the team and learn how you can join the Keller Lab →

 

Keller Lab News

View all →

Knight Campus Building 2 opened to the public on Monday, March 30. Building 2 is part of the second phase of Knight Campus development, a 185,000-square-foot, multi-story bioengineering and applied science research facility.

Get to know one of our newest hires! Therapeutic ultrasound engineer Sara Keller joined the department in January 2026, bringing new techniques and applications for image-guided therapeutic ultrasound.

Set to open in March of 2026, Building 2 of the Phil and Penny Knight Campus for Accelerating Scientific Impact is a dedicated space for world-class research and hands-on training. 

The Keller Lab 

Founded in 2026, the Keller Lab is a therapeutic ultrasound research group within the University of Oregon's Phil and Penny Knight Campus for Accelerating Scientific Impact. Based in the Department of Bioengineering in Eugene, Oregon, the Keller Lab develops image-guided ultrasound technologies for targeted diagnosis and therapy.